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Clinical Trials/ISRCTN31541725
ISRCTN31541725Completed未知

A randomised phase II trial to compare the toxicity, tolerability and activity of 2-drug combinations of the nucleoside analogue reverse transcriptase inhibitors (NRTIs) lamivudine ((-)2'-deoxy-3'thiacytidine, 3tc), zidovudine (ZDV) and 1592U89

Medical Research Council (MRC) (UK)0 sites120 target enrollmentStarted: October 3, 2000Last updated:
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Conditions

Trial Snapshot

Phase
未知
Status
Completed
Sponsor
Enrollment
120
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

2000 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/10776748 2001 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/11531953 2002 Results article in http://www.ncbi.nlm.nih.gov/pubmed/11888583 2002 Results article in http://www.ncbi.nlm.nih.gov/pubmed/12134227 2002 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/12351958 2003 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/12544410 Adherence to prescribed antiretroviral therapy 2007 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/17457088 5 year follow up

Study Design

Study Type
Interventional

Eligibility Criteria

Inclusion Criteria

  • •1. 3 months to 16 years of age
  • •2. Definitive HIV-1 infection

Exclusion Criteria

  • •Not provided at time of registration

Investigators

Sponsor
Medical Research Council (MRC) (UK)

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