Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 87
- 试验地点
- 1
- 主要终点
- use of rocuronium bromide
研究概览
简要总结
To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.
详细描述
Select the patients who will receive posterior lumbar surgery in the Second Hospital of Shanxi Medical University. According to the classification criteria of fat infiltration, it will be divided into three groups: mild, moderate and severe. This study will pump and titrate rocuronium bromide under the monitoring of muscle relaxation during the operation, record the dosage of rocuronium bromide and the duration of pump injection, and evaluate its clinical effect. Postoperative results include the use and clinical effect of rocuronium, which will be counted after the trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18-65; ASA grade I-II; no significant cardiopulmonary disease; no history of surgery in the corresponding surgical area; no coagulopathy.
排除标准
- •refusal to participate by the present experimenter; those with severe cardio-cerebrovascular disease, severe hepatic and renal dysfunction; taking medications affecting the neuromuscular junction; area of monitoring site for skin breakers; patients with intraoperative bleeding, anaphylactic shock, or other serious complications; patients requiring intraoperative neurophysiological monitoring (including sensory, motor evoked potentials).
研究组 & 干预措施
Mild fat infiltration
Fat infiltration rate is less than 30%
干预措施: Rocuronium Bromide (Drug)
Moderate fat infiltration
Fat infiltration rate is 30%~50%
干预措施: Rocuronium Bromide (Drug)
Server fat infiltration
Fat infiltration rate is greater than 50%
干预措施: Rocuronium Bromide (Drug)
结局指标
主要结局
use of rocuronium bromide
时间窗: Perioperative period
average dosage
次要结局
- The general condition of the paraspinal muscle(Perioperative period)
研究者
Zheng Guo
Ph.D.
Second Hospital of Shanxi Medical University