An Exercise Intervention to Improve Overall Brain Health: PEDAL (Physical Education for an Active Lifestyle) Study
Overview
- Phase
- N/A
- Intervention
- Exercise Intervention to improve overall Brain Health
- Conditions
- Brain Care Score
- Sponsor
- University of Alabama at Birmingham
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- Improved overall Brain Care Score metric.
- Status
- Completed
- Last Updated
- 3 months ago
Overview
Brief Summary
The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a body mass index ≥ 25 kg/m2. The main question[s] it aims to answer are:
- To test the effect of moderate vs intensive exercise on Brain Care Score outcomes.
- To ascertain the differential impact of moderate vs high intensity exercise in reducing hypertension and its downstream effects.
Investigators
Pamela G Bowen PhD, CRNP, FNP-BC, BBA
Associate Professor
University of Alabama at Birmingham
Eligibility Criteria
Inclusion Criteria
- •diagnosed with hypertension
- •have a body mass index ≥ 25 kg/m2
- •are between the ages of 35-65 years old
- •access to a smart phone that allows installation of 2 two applications that record your workouts
- •pass a fitness evaluation.
Exclusion Criteria
- •do not have hypertension
- •weight over 300 lbs
- •unable to pass the fitness evaluation
- •BMI less than 25kg/m2
Arms & Interventions
High Intensity Interval Training (HIIT) exercise group,
Participants will be asked to exercise independently 4 days/week for 10 weeks, following a high intensity interval training (HIIT) protocol.
Intervention: Exercise Intervention to improve overall Brain Health
Moderate Intensity Training (MIT) exercise group
Participants will be asked to exercise independently 4 days/week for 10 weeks, following a moderate intensity training (MIT) protocol.
Intervention: Exercise Intervention to improve overall Brain Health
Control exercise group
Participants will be advised to follow the American Heart Association (AHA) guidelines on exercise.
Intervention: Exercise Intervention to improve overall Brain Health
Outcomes
Primary Outcomes
Improved overall Brain Care Score metric.
Time Frame: 10 weeks
The score is based on lifestyle categories on a scale of 0-21 where 21 is best.