DRKS00006295已完成不适用
ocal ablation of liver and lung metastases in patients with colorectal cancer after failure of first- or later-line systemic chemotherapy – a prospective trial - LOCOMOTIVE
niversitätsklinikum Magdeburg0 个研究点目标入组 152 人开始时间: 2016年4月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 152
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •Histologically confirmed colorectal cancer with liver, lung and / or lymph node metastases
- •progression after chemotherapy
- •No more than 2 members with active disease
- •primary tumor resected, no evidence of local recurrence
- •diameter of the largest liver lesion max. 5 cm, not more than five liver metastases
- •Diameter of the largest lesion 15cm, not more than three liver metastases
- •(Satellite metastases near the target lesion excluded)
- •No more than three lung metastases with a diameter of max. 5cm
- •not more than five lesions up to 3 cm diameter
- •No more than two distant metastases outside the lung and liver (except bone metastases)
- •ECOG performance status = 1
- •Karnofsky Index = 70%
排除标准
- •Cerebral metastasis
- •Symptomatic bone metastasis
- •peritoneal, pleural carcinosis
- •Other malignant diseases
- •Life expectancy <6 months
- •violation of an inclusion criterion
研究者
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