HYpertension in the Very Elderly Trial
Completed
- Conditions
- HypertensionCirculatory System
- Registration Number
- ISRCTN14031168
- Lead Sponsor
- British Heart Foundation (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 2100
Inclusion Criteria
1. People 80 years old and above
2. Sustained systolic pressure 160 - 199 mmHg and diastolic (phase V) pressure 90 - 109 mmHg
3. No evidence of renal failure or co-morbidity requiring anti-hypertensive treatment
Exclusion Criteria
Does not comply with above inclusion criteria.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Stroke events (fatal and non-fatal).
- Secondary Outcome Measures
Name Time Method 1. Total mortality<br>2. Cardiovascular mortality<br>3. Cardiac mortality<br>4. Stroke mortality<br>5. Skeletal fracture
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie antihypertensive therapy in very elderly patients as studied in ISRCTN14031168?
How does the trial's intervention compare to standard-of-care calcium channel blockers for geriatric hypertension?
Are there specific biomarkers for predicting treatment response in elderly hypertensive patients from ISRCTN14031168 data?
What adverse events are associated with antihypertensive treatment in the very elderly in ISRCTN14031168?
How do combination therapies involving ACE inhibitors and diuretics perform in elderly hypertension management compared to ISRCTN14031168 findings?