CTIS2023-510186-98-00
Active, not recruiting
Phase 1
DISTINCT: inDividual, targeted thrombosIS prophylaxis versus the standard ‘one size fits all’ approach in patients undergoing Total hIp or total kNee replaCemenT: a national, multicenter, randomized, multi-arm, open-label trial
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Venous thromboembolism
- Sponsor
- Academisch Ziekenhuis Leiden
- Enrollment
- 10078
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects scheduled to undergo an elective Total Hip Arthroplasty or Total Knee Arthroplasty, Subjects aged 18 years or older
Exclusion Criteria
- •Primary arthroplasty for fractures, Patients using thrombocyte aggregation inhibitors that cannot be temporarily discontinued at the discretion of their treating physician, Revision surgery, Hemiarthroplasty, Pregnancy, Current use of therapeutic anticoagulant therapy of any type (e.g., LMWH, DOAC, vitamin K antagonist), A contraindication for either study drug, Insufficient knowledge of the Dutch language, Insufficient mental or physical ability to fulfil trial requirements, Active malignancy (i.e. cancer diagnosis within six months before surgery (excluding basal\-cell or squamous\-cell carcinoma of the skin), recently recurrent or progressive cancer or any cancer that required anti\-cancer treatment within six months before surgery)
Outcomes
Primary Outcomes
Not specified
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