Evaluation of probiotic effect and placebo on reduction of surgical site infection after colectomy
Phase 2
- Conditions
- Colorectal cancer.C18.9 Colon, unspecified, C19 Malignant neoplasm of rectosigmoid junction, C20 Malignant neoplasm of rectum, C21.0 Anus, unspecifiedc18.9, c19
- Registration Number
- IRCT201304187197N7
- Lead Sponsor
- Vice chancellor for research, Ahwaz University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients older than 13 years old with colorectal cancer that came to Razi, Emam Khomeini and Golestan hospital for colectomy between 1390-1391
Exclusion criteria:
1- critically ill patients
2- patients with central venous catheter
3- disrupted mucosal barrier
4- short bowel syndrome
5- abnormal cardiac valves
6- prosthetic valves
7- prosthetic joints
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Surgical site infection. Timepoint: beginning of intervention and first, second, third, tenth and thirtieth days after operation. Method of measurement: fever, respiratory rate, pulse rate, pulse rate, cellulitis, dyscharge.
- Secondary Outcome Measures
Name Time Method WBC/diff. Timepoint: beginning of investigation and 72 hours after surgery. Method of measurement: kit.;IL6. Timepoint: beginning of investigation and 72 hours after surgery. Method of measurement: Bendermed kit.;TNF-a. Timepoint: beginning of investigation and 72 hours after surgery. Method of measurement: Bendermed kit.;CRP. Timepoint: beginning of investigation and 72 hours after surgery. Method of measurement: Roch kit.