Intra-Articular Injection of Etanercept in Patient Suffering From Rheumatoid Arthritis : a Double-Blind Randomized Study

Phase 3

Completed

• Conditions: Rheumatoid Arthritis
• Interventions: Procedure: intra-articular injection of etanercept; Procedure: intra-articular injection of steroid

• Registration Number: NCT00522184
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Intra-articular injection of etanercept in patient suffering from rheumatoid arthritis: a double-blind randomized study for evaluation of efficacy and safety of etanercept versus intra-articular steroid injection in acute synovitis (knee,wrist,ankle,elbow)

Detailed Description

Not available

Study Timeline

• Study Start: 2005-02
• Study Completion: 2006-11
• Status Verified: 2007-08
• Study First Submitted: 2007-08-27
• Study First Submitted QC: 2007-08-27
• Last Update Submitted: 2007-08-27
• Study First Posted: 2007-08-29
• Last Update Posted: 2007-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• must be able to understand the information about the study
• diagnosis of rheumatoid arthritis for 6 month at least
• suffering for 2 weeks at least
• with evaluation of pain over 4/10
• with stable DMARDs treatment for three month at least

Exclusion Criteria

• infection or surgery on the target joint
• treated with infliximab,adalimumab or anakinra

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	intra-articular injection of etanercept	patient receiving etanercept intra-articular injection
2	intra-articular injection of steroid	patient receiving steroid intra-articular injection

Primary Outcome Measures

Name	Time	Method
Pain	every month during six month

Trial Locations

Locations (1)

Rheumatology department, Hopital Archet I; 🇫🇷 Nice, France