Comparative Evaluation Of Sodium Fluoride Varnish , Diode Laser and Their Combination To Reduce Dental Hypersensitivity: A Randomized Clinical Study.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Reduction in post-opeative sensitivity after use of flouride varnish and diode laser .
研究概览
简要总结
Dentin hypersensitivity is characterized by short, sharp pain arising from exposed dentin in response to stimuli, typically thermal, evaporative, tactile, osmotic or chemical and which cannot be ascribed to any other dental defect or pathology. Dentin hypersensitivity can range from slight discomfort to extreme pain depending on the individual’s pain perception and tolerance. A variety of desensitizing agents have been recommended to reduce dentin hypersensitivity, which include nerve-desensitizing agents, protein-precipitating agents, dentin adhesive sealers, agents plugging dentinal tubules, and homeopathic agents.Sodium fluoride (NaF) was first proposed as a desensitizing agent by Lukomsky. Fluoride varnish was also favored by Porto et al. due to its ease of application and immediate action.In 1985, lasers were introduced as a potential desensitizing tool. The working parameters such as wavelength and the power density of the laser and the optical properties of the target tissue can lead to different tissue reactions.. FluoroDip Bioactive is an alcoholic suspension of sodium fluoride and bio-glass in natural shellac with artificial flavoring. 1 ml of FluoroDip Bioactive varnish contains 50mg of sodium fluoride equivalent to 22.6 mg of fluoride.The interaction of laser with tissue leads to 17tissue reactions, which vary according to the laser wavelength and amount of energy applied.The mechanism of action for DH treatment consists of the chemical capacity of fluoride in reducing the fluid movements in the dentin tubules by means of the deposit of minerals on the open dentin tubules.Till date, numerous agents have been tried to eliminate this unpleasant symptom, in the form of mouthwashes, dentifrices, gel, ionic exchange gadgets (iontophoresis), etc. However, none of these agents are capable of delivering the drug constantly for long periods and require frequent revisits by patients or may take a long time to provide relief.Hence, the present study aimed to clinically evaluate the efficacy of 5% NaF varnish and 980 nm diode laser (DL) irradiation alone and in comparison with the combination of NaF varnish and 980 nm DL in the management of DH.Thus, this study aimed to assess the effectiveness of sodium fluoride varnish and diode laser and their combination to reduce dentinal hypersensitivity**.**
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy both male and female patients between 18-70 years of age will be included in the study.
- •Patients with good oral hygiene, and clinically demonstrable dentinal hypersensitivitywill be included in the study.
- •Participants who have more than two sensitive teeth with a Schiff sensitivity score of ≥ 2 will be included in the study.
- •Patients with pre-operative VAS scoresof more than 3 on application of air/ cold will be included in the study.
排除标准
- •Patients allergic to sodium fluoride or known allergy to any toothpaste containing fluoride will be excluded from the study.
- •Patients with any systemic or psychological diseases, constant use of analgesics, anti-inflammatory drugs, or allergic responses to dental products will be excluded from the study.
- •Teeth with carious lesions, defective restorations, fractures, prosthesis or orthodontics appliances, periodontal pockets, mobility, or evidence of pulpits will be excluded from the study.
- •In addition, those who have used any desensitizing agents or undergone any periodontal surgery in the last 6 months were excluded from the study
- •Patientstaking any analgesics, antibiotics, sedatives, and anti-anxiety drugs on regular basis or before 24 hours of treatment will be excluded.
- •Pregnant and lactating patients will be excluded from study.
结局指标
主要结局
Reduction in post-opeative sensitivity after use of flouride varnish and diode laser .
时间窗: 24 hours and 1 week
次要结局
未报告次要终点
研究者
DEVASHREE
K M shah dental college