Development of Frailty Prevention Clinic in Geriatric Comprehensive Clinic RSCM:

Not Applicable

• Conditions: Frailty; Resistance Training; Sarcopenia
• Interventions: Procedure: Resistance Training; Procedure: Standard Therapy

• Registration Number: NCT05511311
• Lead Sponsor: Indonesia University

Brief Summary

There is an increasing number of elderly population, not only in Indonesia, but also in the world. With increasing of age, there is also an increasing number of elderly with sarcopenia and frailty. Both of the diseases can lead to dependency, decrease quality of life, and morbidity. Besides nutrition, physical activity, especially resistance training is proven to be beneficial in improving sarcopenia and frailty condition.

Currently in Cipto Mangunkusumo National Hospital (RSCM), there is no comprehensive frailty prevention clinic in the geriatric inpatient clinics. This research can be the base of frailty and sarcopenia treatment in RSCM.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-01
• Status Verified: 2022-08
• Study First Submitted: 2022-08-17
• Study First Submitted QC: 2022-08-19
• Last Update Submitted: 2022-08-19
• Study First Posted: 2022-08-22
• Last Update Posted: 2022-08-22
• Primary Completion: 2022-10-31
• Study Completion: 2022-11-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 220

Inclusion Criteria

• Patients 60 years old or orlder
• Categorized as Pre-frail or Frail based on FRAIL criteria
• Is not in routine physical activity in the past 3 months
• Succeeded Mini Physical Performance Test with score 11 or more

Exclusion Criteria

• Cognitive Disturbance (Abbreviated Mental Test < 8)
• Not consenting to join the trial

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	Resistance Training	12-week of Resistance Training developed by RSCM using sand-bag
Control	Standard Therapy	12-week of Standard Therapy using elastic-band

Primary Outcome Measures

Name	Time	Method
Frailty Status	12 weeks	The FRAIL scale includes 5 components: Fatigue, Resistance, Ambulation, Illness, and Loss of weight (10). Frail scale scores range from 0-5 (i.e., 1 point for each component; 0=best to 5=worst) and represent frail (3-5), pre-frail (1-2), and robust (0) health status
Sarcopenia Status	12 weeks	Measured using: * BIA: \<7.0 kg/m2 in men and \<5.7 kg/m2 in women; * Five times sit to stand: ≥12 seconds; * Hand-grip strength: \<28 kg for men and \<18 kg for women
Walking Speed	12 weeks	\<1.0 m/s
Patient's Quality of Life	12 weeks	Measured by EQ-5D: ranging from 0 ('worst imaginable health') to 100 ('best imaginable health')

Secondary Outcome Measures

Name	Time	Method
Prevalence of Frailty	12 weeks	The FRAIL scale includes 5 components: Fatigue, Resistance, Ambulation, Illness, and Loss of weight (10). Frail scale scores range from 0-5 (i.e., 1 point for each component; 0=best to 5=worst) and represent frail (3-5), pre-frail (1-2), and robust (0) health status
Prevalence of Sarcopenia	12 weeks	Measured using: * BIA: \<7.0 kg/m2 in men and \<5.7 kg/m2 in women; * Five times sit to stand: ≥12 seconds; * Hand-grip strength: \<28 kg for men and \<18 kg for women

Trial Locations

Locations (1)

Cipto Mangunkusumo National Hospital; 🇮🇩 Jakarta, Jakarta Pusat, Indonesia