NCT02853188已完成不适用
Does the Measure of the Plasma Tissue Factor Allow to Predict a Venous Thromboembolism Episode for Patients Presenting a Primitive Lung Cancer?
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Hopital Foch
- 入组人数
- 315
- 试验地点
- 10
- 主要终点
- Tissue factor
研究概览
简要总结
The aim of the study is to evaluate if the plasma activity of the tissue factor at the time of the diagnosis of a lung cancer, before any treatment, or after the treatment of induction (surgery or two first cures of chemotherapy), can be a predictive factor of venous thromboembolism disease in the year which follows the diagnosis, independently of the other parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of more than 18 years old
- •Patients with cancer of lung diagnosis carried for less than 2 months and which were not handled yet, either by surgery or by chemotherapy, or by radiotherapy
- •Patients whose life expectancy is considered 3-month-old a superior
- •Patients having given writed consent
- •Patients affiliated to a national insurance scheme or benefiting from such a diet
- •Patients having received a treatment (processing) anticoagulating in preventive dose if this treatment was stopped at least 3 days before the 1st taking or patients not receiving an anticoagulating treatment (in case of curative treatment, the latter was before arrested at least 3 months
排除标准
- •Patients having a hepatic disease with coagulation disorders
- •Patients under anticoagulants with dose guardian in 3 months preceding the study or presenting an active infection
- •Patients having a history of other cancer considered as cured and diagnosed for less than 5 years (with the exception of the patients operated for an in situ carcinoma of the neck of the womb or the patients having undergone the excision of a squamous-cell carcinoma)
研究组 & 干预措施
cancer of lung
Experimental
干预措施: venous thromboembolism (Other)
结局指标
主要结局
Tissue factor
时间窗: 2 years
Tissue factor is measured by kinetic-chromogenic assay
Venous thromboembolism occurence
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (10)
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