The protective effects of Gonadotropin releasing hormone agonist (GnRHa) in preventing the chemotherapy induced ovarian damage and transgenerational effects
Not Applicable
- Conditions
- Health Condition 1: N971- Female infertility of tubal originHealth Condition 2: O94-O9A- Other obstetric conditions, not elsewhere classified
- Registration Number
- CTRI/2020/11/029313
- Lead Sponsor
- Indian Council of Medical Research ICMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Infertile females with age more than 22 years and less than 35 years
Exclusion Criteria
Infertile females with age less than 22 years and more than 35 years
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response of Granulosa cells to chemotherapy and GnRHa (Gonadotropin releasing hormone agonist)Timepoint: The outcome will be assessed after 24 hour in-vitro culture
- Secondary Outcome Measures
Name Time Method Protective effect of GnRHa (Gonadotropin releasing hormone agonist) on Granulosa cells which was exposed to chemotherapyTimepoint: The protective effect will be assessed after 24 hour in-vitro exposure