Respiratory Training in Patients With Leukemia
- Conditions
- Leukemia
- Interventions
- Other: respiratory training
- Registration Number
- NCT03876834
- Lead Sponsor
- Cairo University
- Brief Summary
Forty male leukemic patients receiving chemotherapy were selected from National Cancer Institute, They were randomly assigned into two groups. Group (A) included 30 patients who were trained by Inspiratory muscle trainer for 4 weeks ;5 sessions/week and Group (B) included 10 patients as a control group.
The following measures were taken before and after the study period : Maximum voluntary ventilation(MVV) , 2 min walk test, FACT-G questionnaire
- Detailed Description
Forty male leukemic patients receiving chemotherapy for at least one cycle and their mean ages 37.1 ± 4.89 years.The patients were selected from National Cancer Institute, Cairo ( inpatient ward). The study lasted from March 2018 to June 2018. Patients were randomly assigned into two groups.Group A (30 patients) who received inspiratory muscles training for 4 successive weeks, 5 sessions/week; and Group B (10 patients) acted as a control group on chemotherapy only. Data obtained from both groups regarding (MVV), 2 min walk test and Quality of life questionnaire (FACT-G) were statistically analyzed and compared
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 40
- male patient with age ranges from 30-50 years
- All patients were leukemic receiving chemotherapy for at least one cycle as a treatment of malignant tumor
- All patients were hemodynamically stable
- All patients were ambulant
- lung cancer
- History of any pulmonary disease.
- Metastasis of lungs, ribs, mediastinal structure
- Pulmonary pathology(e.g acute respiratory distress syndrome or exacerbation of chronic obstructive pulmonary disease)
- ruptured ear drum or any other condition of the ear
- High peak airway pressure (barotraumas)
- patients with marked elevated left ventricular end diastolic volume and pressure
- patients with worsening heart failure signs and symptoms
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description study group (group A) respiratory training Group (A) included 30 leukemic patients receiving chemotherapy in addition to training by inspiratory muscle trainer(IMT) for 4 weeks, 5 sessions /week
- Primary Outcome Measures
Name Time Method Maximum voluntary ventilation change from baseline maximum voluntary ventilation at 4 weeks It was performed by breathing deeply and rapidly for 10 to 15 seconds using spirometer
2 min walk test change from baseline 2 min walk test at 4 weeks Each patient was asked to cover as much ground as possible over 2 minutes
FACT-G questionnaire change from baseline FACT-G questionnaire at 4 weeks 27 questions with four domains assessing physical well being,social well being, emotional well being and functional wellbeing
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of Physical Therapy
🇪🇬Cairo, Egypt