CTRI/2022/04/041726已完成不适用
“Comparison of intrathecal hyperbaric Ropivacaine 0.75% and hyperbaric Bupivacaine 0.5% in lower limb orthopaedic surgery-A prospective randomised double blind comparative studyâ€
Department of Anaesthesiology1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2022年4月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Duration of Analgesia
研究概览
简要总结
Our original study is comparison of intrathecal 0.5 % bupivacaine heavy and 0.75% ropivacaine heavy for lower limb surgeries in terms of duration of analgesia, block characterstics. kindly consider our study for ctri registration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASA physical status Grade I and II of either sex.
- •Patients in the age group of 18-60 years.
- •Posted for lower limb orthopedic surgeries under spinal anaesthesia.
排除标准
- •Patients posted for emergency surgeries.
- •Pregnant patients.
- •Patients having coagulation abnormalities, platelet count <75,000, INR >1.5, or on anticoagulants.
- •Patients having systemic illness (severe hypovolemia, raised intracranial pressure, neuromuscular diseases, ischemic/ valvular/ congenital heart diseases, psychiatric, hematological disorder).
- •Patients having any absolute contraindications for spinal anesthesia.
- •Any allergy to study drugs or local anaesthetic drugs.
- •Short stature (height <150cms), with spinal deformity.
结局指标
主要结局
Duration of Analgesia
时间窗: 4 hours postoperatively
次要结局
- onset and duration of sensory block, onset and duration of motor block and hemodynamic parameters.(Intraoperative (3-4 hours))
研究者
研究点 (1)
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