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临床试验/NCT01840514
NCT01840514Unknown不适用

Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.

Mansoura University2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2012年12月最近更新:
适应症

试验速览

阶段
不适用
入组人数
60
试验地点
2
主要终点
hemodynamic monitoring

研究概览

简要总结

The stress of orthotopic living donor liver transplantation in patients with cirrhosis could induce worsening of an already recorded myocardial dysfunction or may be associated with a new myocardial dysfunction in patients previously having normal myocardial functions, therefore this study will be designed for intra-operative detection of new onset ventricular dysfunction or worsening of already diagnosed ventricular dysfunction in living donor liver transplant recipient and the possible contribution of several hemodynamic and oxygenation parameters in the generation of any cardiovascular function impairment will be also investigated and to determine the impact of ventricular dysfunction on early (7 PO days) graft function, 28 days survival and patient outcomes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • all adult recipient

排除标准

  • massive blood transfusion
  • grade III esophageal varices

结局指标

主要结局

hemodynamic monitoring

时间窗: intraoperative

次要结局

  • graft function(7 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amr Mohamed Yassen

professor

Mansoura University

研究点 (2)

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