A study to find out the volume of the contents of the stomach in patients with kidney failure and fasting before undegoing surgery

Not yet recruiting

Conditions: End stage renal disease,

Registration Number: CTRI/2019/11/022139

Lead Sponsor: MS Ramaiah Medical College

Brief Summary: Pulmonaryaspiration of gastric contents is a serious perioperative complication. TheFourth National Audit Project by the Royal College of Anaesthetists hasreported pulmonary aspiration as the cause of more than 50% of airway-relateddeaths in anaesthesia. The resulting respiratory compromise isthought to be related to both volume and nature of the aspirate. The most commonly used measure to prevent aspiration is fasting beforeanaesthesia, and anaesthesia societies have developed guidelines forpreoperative fasting. However, these guidelines apply to healthypatients undergoing elective surgery and not reliable in patients withco-morbidities that affect gastric emptying. Gastricemptying is known to be delayed in patients with end-stage renal failure.Though certain biochemical markers have been shown to be associated with delayedgastric emptying in patients with chronic renal failure, there is no acceptablemethod of identifying such patients before anaesthesia. Gastricultrasound has recently evolved into a simple, point-of-care tool forevaluating gastric content and volume. The gastric antrum can be easilyidentified using a low frequency curvilinear probe. By visualising the antrum,not only the contents of the stomach can be determined, but also quantificationis possible by application of suitable validated methods. There ispaucity of literature with respect to the use of gastric ultrasound todetermine residual volume in patients with end-stage renal failure. Hence, thepresent study is designed to evaluate the gastric contents and volume inpatients with end-stage renal failure by gastric ultrasound.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 186

Inclusion Criteria

Age 20-60 years Body mass index < 40kg/m2 End-stage renal failure.

Exclusion Criteria

History of upper gastrointestinal disease Previous surgery on esophagus or stomach Previous upper abdominal surgery Pregnancy.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To calculate the gastric residual volume and nature of gastric contents	To calculate the gastric residual volume and nature of gastric contents 30 min before anaesthesia induction

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): MS Ramaiah Medical Teaching Hospital
🇮🇳
Bangalore, KARNATAKA, India
MS Ramaiah Medical Teaching Hospital
🇮🇳Bangalore, KARNATAKA, India
DrSushma K
Principal investigator
9945517222
sushmakothapalli55@gmail.com