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临床试验/CTRI/2019/11/022139
CTRI/2019/11/022139尚未招募不适用

Ultrasound evaluation of gastric residual volume in fasting end-stage renal failure patients

MS Ramaiah Medical College1 个研究点 分布在 1 个国家目标入组 186 人开始时间: 2019年1月12日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
186
试验地点
1
主要终点
To calculate the gastric residual volume and nature of gastric contents

研究概览

简要总结

Pulmonaryaspiration of gastric contents is a serious perioperative complication. TheFourth National Audit Project by the Royal College of Anaesthetists hasreported pulmonary aspiration as the cause of more than 50% of airway-relateddeaths in anaesthesia. The resulting respiratory compromise isthought to be related to both volume and nature of the aspirate. The most commonly used measure to prevent aspiration is fasting beforeanaesthesia, and anaesthesia societies have developed guidelines forpreoperative fasting. However, these guidelines apply to healthypatients undergoing elective surgery and not reliable in patients withco-morbidities that affect gastric emptying. Gastricemptying is known to be delayed in patients with end-stage renal failure.Though certain biochemical markers have been shown to be associated with delayedgastric emptying in patients with chronic renal failure, there is no acceptablemethod of identifying such patients before anaesthesia. Gastricultrasound has recently evolved into a simple, point-of-care tool forevaluating gastric content and volume. The gastric antrum can be easilyidentified using a low frequency curvilinear probe. By visualising the antrum,not only the contents of the stomach can be determined, but also quantificationis possible by application of suitable validated methods. There ispaucity of literature with respect to the use of gastric ultrasound todetermine residual volume in patients with end-stage renal failure. Hence, thepresent study is designed to evaluate the gastric contents and volume inpatients with end-stage renal failure by gastric ultrasound.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Age 20-60 years Body mass index < 40kg/m2 End-stage renal failure.

排除标准

  • History of upper gastrointestinal disease Previous surgery on esophagus or stomach Previous upper abdominal surgery Pregnancy.

结局指标

主要结局

To calculate the gastric residual volume and nature of gastric contents

时间窗: To calculate the gastric residual volume and nature of gastric contents 30 min before anaesthesia induction

次要结局

未报告次要终点

研究者

申办方类型
Private medical college

研究点 (1)

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