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临床试验/CTRI/2025/10/096296
CTRI/2025/10/096296尚未招募4 期

A comparative evaluation of ultrasound guided anterior quadratus lumborum block with posterior quadratus lumborum block for total laparoscopic hysterectomy.

ASIAN INSTITUTE OF MEDICAL SCIENCES1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2025年11月10日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
56
试验地点
1
主要终点
To compare the time to first rescue analgesic requirement after anterior versus posterior quadratus lumborum block in patients undergoing total laparoscopic hysterectomy.

研究概览

简要总结

This prospective, randomized, double-blind, controlled clinical trial aims to compare the analgesic efficacy of two ultrasound-guided approaches of the quadratus lumborum block (QLB)—anterior  and posterior—in patients undergoing total laparoscopic hysterectomy (TLH) under general anaesthesia.

A total of 56 female patients (ASA I–II, aged 40–65 years) scheduled for elective TLH will be randomly assigned into two equal groups. Group A will receive ultrasound-guided anterior QL block, while Group B will receive posterior QL block, both using 25 mL of 0.3% ropivacaine bilaterally with 8 mg dexamethasone.

Blocks will be performed post-induction by experienced anaesthesiologists. The primary outcome is the time to first rescue analgesic requirement . Secondary outcomes include total opioid consumption within 24 hours, VAS pain scores, postoperative nausea/vomiting, sedation, and patient satisfaction scores.

The study seeks to determine whether anterior QLB provides superior postoperative analgesia and greater patient satisfaction compared to the posterior approach, potentially supporting its routine use for enhanced recovery after total laparoscopic hysterectomy.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant, Investigator and Outcome Assessor Blinded

入排标准

年龄范围
40.00 Year(s) 至 65.00 Year(s)(—)
性别
Female

入选标准

  • Female patients aged 40–65 years, belonging to ASA physical status I–II, undergoing elective total laparoscopic hysterectomy under general anaesthesia will be included for this trial.

排除标准

  • 未提供

结局指标

主要结局

To compare the time to first rescue analgesic requirement after anterior versus posterior quadratus lumborum block in patients undergoing total laparoscopic hysterectomy.

时间窗: 0-24 hours

次要结局

  • To compare total opioid consumption within 24 hours postoperatively.

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

DIVESH ARORA

Asian Hospital Faridabad

研究点 (1)

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