Can adequacy of anesthesia depth and quality of recovery be influenced by the level of neuromuscular blockade: a randomized controlled study assessing propofol and remifentanil requirements and quality of recovery in patients with a standard practice of non-deep rocuronium neuromuscular blockade versus deep neuromuscular blockade reversed with sugammadex.

Centro Hospitalar do Porto0 sites70 target enrollmentMarch 11, 2015

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Seventy patients with an ASA score of I to III, 18 to 80 years old, scheduled for routine anterior cervical spine surgery in the Centro Hospitalar do Porto will be enrolled.
Sponsor: Centro Hospitalar do Porto
Enrollment: 70
Status: Active, Not Recruiting
Last Updated: 6 years ago

No summary available.

Registry

who.int

Start Date

March 11, 2015

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional clinical trial of medicinal product

Sponsor

Centro Hospitalar do Porto

•1\.Patients ASA I\-III
•2\.Between 18 – 80 years old
•3\.Scheduled for routine cervical surgery
•4\.Minimum duration of surgery is 90 minutes and performed with total intravenous anaesthesia (TIVA) with the hypnotic propofol, the analgesic remifentanil and the neuromuscular relaxant rocuronium
•5\.Patients that are able to and do provide a signed informed consent form
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range 50
•F.1\.3 Elderly (\>\=65 years) yes

•1\.Patients with neuromuscular diseases and severe cardiac and respiratory pathologies
•2\.Contra indication for any of the drugs used
•3\.Not able to complete the baseline PQRS test.
•4\.Indication to perform tracheal intubation using fibroscopy
•5\.Patients who are pregnant or nursing