Investigating the Hidden Link Between Meatal Stenosis and Primary Nocturnal Enuresis in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Association between Meatal Stenosis and primary nocturnal enuresis
研究概览
简要总结
This study aimed to investigate the association between meatal stenosis and primary nocturnal enuresis severity, and evaluated therapeutic outcomes following surgical correction.
详细描述
Primary nocturnal enuresis (PNE) is a prevalent pediatric condition characterized by involuntary urination during sleep in children aged five years or older who have never achieved consistent nighttime dryness. The prevalence of PNE decreases with age, affecting approximately 15% of five-year-old and decreasing to 1-2% by adolescence.
Meatal stenosis, defined as the pathological narrowing of the urethral meatus, is an underexplored potential factor. This condition is known to cause obstructed urinary flow, incomplete bladder emptying, and increased bladder pressure, all of which may contribute to enuresis.
The incidence of meatal stenosis is higher in circumcised males but can also occur in uncircumcised males and females due to inflammation, trauma, or infection
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 7 Years 至 12 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male children aged 7-12 years.
- •Diagnosed with primary nocturnal enuresis.
- •Evaluated and treated at the study center between January 2021 and December
- •Confirmed diagnosis of meatal stenosis based on clinical examination and uroflowmetry when indicated.
- •Patients who underwent meatoplasty and completed the prescribed follow-up period.
排除标准
- •Secondary enuresis (previously dry for ≥ 6 months before recurrence of bedwetting).
- •Known neurological disorders (e.g., spina bifida, cerebral palsy) or developmental delays.
- •Structural anomalies of the urinary tract other than meatal stenosis (e.g., posterior urethral valves, vesicoureteral reflux).
- •Children who did not complete the follow-up or had incomplete clinical records.
研究组 & 干预措施
Study group
Patients who underwent meatoplasty.
干预措施: Meatoplasty Primary nocturnal enuresis. (Procedure)
结局指标
主要结局
Association between Meatal Stenosis and primary nocturnal enuresis
时间窗: 3 years from collecting the data from the database
Association between Meatal Stenosis and primary nocturnal enuresis was assessed to determine whether there is a significant relationship between the presence of meatal stenosis and the occurrence of primary nocturnal enuresis in male children aged 7-12 years.
次要结局
- Resolution of primary nocturnal enuresis post-meatoplasty(3 years from collecting the data from the database)
- Need for Revision Meatoplasty(3 years from collecting the data from the database)
- Prevalence of Meatal Stenosis in primary nocturnal enuresis patients(3 years from collecting the data from the database)
- Incidence of complications(3 years from collecting the data from the database)
研究者
Waheed Fawzy Abdelrasol
Lecturer of Urology, Faculty of medicine, New Vally University, New Vally, Egypt
New Valley University