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Tumor Registry of Lymphatic Neoplasia

Completed
Conditions
Non-Hodgkin's Lymphoma (NHL)
Chronic Lymphocytic Leukemia (CLL)
Multiple Myeloma (MM)
Registration Number
NCT00889798
Lead Sponsor
iOMEDICO AG
Brief Summary

The purpose of this registry is to record information on therapy reality of malignant lymphatic systemic diseases by office-based haematologists in Germany.

Detailed Description

The TLN is a prospective, longitudinal, nation wide cohort study with the purpose to record information on the antineoplastic treatment of lymphatic neoplasms in Germany. The registry will follow patients for up to five years. It will identify common therapeutic sequences and changes in the treatment of the disease. At inclusion, data in patient characteristics, comorbidities, tumor characteristics and previous treatments are collected. During the course of observation data on all systemic treatments, radiotherapies, surgeries, and outcome are documented.

The impact of nutrition (LyNut) and physical activity (LyNut) on the course of the adjuvant disease will be examined in patients with indolent and aggressive Non-Hodgin Lymphoma, as well as long-term effects of systemic treatment (LyTox) and quality of life (LyLife) in patients with multiple myeloma.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3795
Inclusion Criteria
  • Confirmed diagnosis of Non-Hodgkin's lymphoma, chronic lymphocytic leukaemia or multiple myeloma
  • Must receive a first- or second-line therapy
  • 18 years or older
  • Signed, written informed consent
Exclusion Criteria
  • no systemic therapy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Course of treatment (treatment reality)5 years per patient

Documentation of anamnestic data and therapy sequences

Secondary Outcome Measures
NameTimeMethod
Effectiveness of treatment5 years per patient

Documentation of response rates and progression-free survival per therapy sequence, overall survival time and adverse reactions

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