In patients undergoing ultrasound-guided fascia iliaca compartment blockade before knee replacement surgery, does the addition of hyaluronidase to the local anaesthetic solution improve the success rate and hasten the onset of the nerve blockade?

Phase 4

• Conditions: Improving regional anaesthesia efficacy; Anaesthesiology - Anaesthetics; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12612000401853
• Lead Sponsor: Dr Andrew Kenneth Lansdown

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-04-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients undergoing single-sided, first-time total knee replacement
Male or female; 18-80 years of age at the time of surgery
Must be able to understand the possible anaesthetic complications and study protocol

Exclusion Criteria

Any refusal/contraindication to fascia iliaca compartment block
Allergy to study medications
Pregnancy
Inability to communicate with authors
Morbid obesity [Body Mass Index (BMI) > 35kg/m2]
Known hepatic or renal insufficiency
Pre-existing neurological deficit of lower limbs

Study & Design

• Study Type: Interventional
• Study Design: Not specified