EUCTR2010-019469-26-GB
Active, not recruiting
Phase 1
se of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre placebo controlled randomised trial of a calcium channel blocker(nifedipine)and an alpha blocker(tamsulosin) - The SUSPEND trial - Symptomatic ureteric stone passage enabled by drugs (SUSPEND)
niversity of Aberdeen0 sites1,167 target enrollmentJune 18, 2010
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- se of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: multicentre placebo controlled randomised trial of a calcium channel blocker(nifedipine) and an alpha blocker (tamsulosin).
- Sponsor
- niversity of Aberdeen
- Enrollment
- 1167
- Status
- Active, not recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients presenting acutely with ureteric colic
- •Adults \=18 to \= 65 years of age
- •Presence of stone confirmed by non\-contrast computed tomography of the kidney, ureter and bladder (CTKUB), or by IVU (intravenous urogram) with subsequent CTKUB confirmation within 12 hours
- •Stone within any segment of the ureter
- •Unilateral ureteric stone
- •Largest dimension of the stone \=10 mm
- •Female subjects must be post menopausal (defined as 12 months with no menses without an alternative medical cause), permanently sterilised or willing to use two methods of contraception listed in the protocol prior to the start of dosing until at least 28 days after receiving the last dose of trial medication
- •Capable of giving written informed consent, which includes compliance with the requirements of the trial
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
Exclusion Criteria
- •Women who have a known or suspected pregnancy (confirmed by a pregnancy test)
- •Women who are breast\-feeding
- •Asymptomatic incidentally found ureteric stone
- •Stone not confirmed by CTKUB
- •Stone with any one dimension \>10 mm
- •Kidney stone without the presence of ureteric stone
- •Multiple (i.e. \= 2\) stones within ureter
- •Bilateral ureteric stones
- •Stone in a ureter draining a solitary kidney (either anatomically or functionally)
- •Patients with abnormal renal tract anatomy (such as a duplex system, horseshoe kidney or ileal conduit)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 3
Spontaneous Urinary Stone Passage ENabled by DrugsISRCTN69423238niversity of Aberdeen (UK)1,200
Active, not recruiting
Phase 1
Pharmaco-epidemiology of the treatment of the symptomatic pulmonary embolism among in-patients and 75 years old or more: prospective, multicentric PEAGE cohortEUCTR2013-000315-24-FRCHU SAINT-ETIENNE1,500
Active, not recruiting
Not Applicable
Sympthomatic and prophylactic treatment of drug induced oral dryness in elderly patients with high drug consumption. - Drug induced oral drynessOral dryness is a common problem with serious consquences, especially among elderly individuals. The most common reason for oral dryness is drug consumption. Research has shown that an individual with more than 5 prescribed drug is at risk for oral problems. Drug consumtion is increasing among elderly, mostly due to lack in cooperation in the health care system. Oral dryness have impact on quality of life with eating difficulties and an increased rsik for dental caries.EUCTR2006-001468-21-SEKarolinska Institutet
Not yet recruiting
Not Applicable
Treatment and adverse effects of medications used for sleeplessness in elderly patientsHealth Condition 1: F068- Other specified mental disorders due to known physiological conditionCTRI/2022/11/047378Varun Santhosh
Completed
Phase 2
Comparison of efficacy of oral Levamisole and Formoterol+Budesonide inhaler with standard treatment of Corona infection.IRCT20200324046852N1Fasa University of Medical Sciences30