se of Thiamine supplementation versus placebo on the cardiac function in chronic heart failure patients referred to the cardiology clinic of Imam Khomeini Hospital
Not Applicable
- Conditions
- Congestive Heart Failure.Congestive heart disease
- Registration Number
- IRCT201311019768N2
- Lead Sponsor
- Imam Khomeini hospital, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Inclusion: Consent to take part in the study; Treatment with Furosemide; Known case of congestive heart faiure with ejection fraction<40% and at least on of these criteria: 1-Dyspnea or orthopnea, 2- Positive hepatojugular reflux, 3- Interstitial transudation in the chest X-ray. 4- Brain natriuretic peptide (BNP)=>39 ng/L.
Exclusion: 1-Acute heart failure; Vitamine supplementation at the time of first visit; Renal insufficiency (serum creatinine>250 micromol/L; pregnancy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ejection fraction increase. Timepoint: 1 month and 3 months after recruitment. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method Improvement in the clinical symtoms. Timepoint: 1 and 3 months after recruitment. Method of measurement: Interview and physical excmination.