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临床试验/NCT00967278
NCT00967278已完成不适用

Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting

University of Sao Paulo1 个研究点 分布在 1 个国家开始时间: 2009年8月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
试验地点
1

研究概览

简要总结

The purpose of this study is to study the positioning and stabilization of different cardiac walls performed during off-pump coronary artery bypass grafting (CABG) may have dissimilar impact on hemodynamics.

The objective is to evaluate hemodynamics during distal coronary anastomoses in different cardiac walls.

详细描述

  • Twenty patients undergoing off-pump CABG monitored with pulmonary artery catheter and esophageal doppler will be enrolled.
  • Patients with a left ventricular ejection fraction <50%, age >80 yr, creatinine >1.4 mg/dl, reoperation, valvular heart disease or chronic obstructive pulmonary disease were excluded
  • Data will be collected after volemic and hemodynamic adjustments, after heart positioning and establishment of a suction stabilizer and before its removal in anterior, lateral or posterior wall artery anastomosis.
  • Data was compared by means of two-way repeated measures ANOVA.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
— 至 80 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Normal left ventricular function
  • Minimal to moderate surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)

排除标准

  • Patients with a left ventricular ejection fraction <50%,
  • Age >80 yr
  • Creatinine >1.4 mg/dl
  • Reoperation
  • Valvular heart disease
  • Chronic obstructive pulmonary disease
  • High surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)

研究者

申办方类型
Other

研究点 (1)

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