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临床试验/NCT00210418
NCT00210418已完成不适用

Prevention or Cure: A Comparison of the Effectiveness of Targeting Food Supplements to Malnourished Children Compared to Universal Targeting of Children Under Two in Haiti

International Food Policy Research Institute1 个研究点 分布在 1 个国家目标入组 1,500 人开始时间: 2002年5月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
1,500
试验地点
1
主要终点
Prevalence of undernutrition (stunting, wasting, underweight) two years after implementation of intervention

研究概览

简要总结

The objective of this study is to compare two approaches to targeting donated supplementary food to young children. The study compares the effectiveness of the widely-used curative approach where targeting is based on the child's poor nutritional status to a preventive approach which targets children in poor communities solely on the basis of age and provides supplementary food to all children aged 6-23 months. Cost-effectiveness of the two targeting approaches will also be assessed.

详细描述

Under-nutrition is widespread among young children in poor countries. In many countries one of the programmatic responses has been distribution of supplementary food to under-nourished children and, often, their families. Traditionally, children under five years have been identified based on low weight-for-age or other anthropometric indicators, and those below a certain cut-off have received supplements. Typically this results in supplementation of many children in the 3-5 year age range, since they are most likely to display cumulative deficits in height and weight, and thus fall below the chosen cut-off.

However, there has been increasing evidence that the most effective period to ensure benefit from supplementary food is when children are 6 to 24 months of age. This is the period of highest growth velocity among humans and thus a period when most growth faltering occurs.

Based on this evidence, the current study aims to assess the effectiveness and cost-effectiveness of a preventive approach that targets children under 24 months as compared to the traditional "curative" approach that targets malnourished (and usually older) children under the age of 5 years.

The comparison is made in the programmatic context of a US Title II food aid distribution program implemented by an international non-governmental organization in rural Haiti. This programmatic context is common in many countries that receive assistance from the United States Agency for International Development and other donors. The study has also involved development of new nutrition education materials and tools, aimed at enabling caregivers to prevent malnutrition. In addition, a range of program operational issues will be studied in order to yield results useful to other implementers of similar interventions.

Comparison: Comparisons will be made at the level of the program site, with service delivery points randomized either to target food supplements as in the past, based on the child's nutritional status, or to target preventively based on age. Pregnant women and lactating women with infants under 6 months of age will receive supplements under both targeting models. Effectiveness will be assessed based on two cross-sectional surveys, at baseline and two years after full implementation of the program.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Family resides in community served by World-Vision Haiti's Maternal and Child Health and Nutrition Program

排除标准

  • 未提供

研究组 & 干预措施

Recuperative targeting

Active Comparator

This arm targeted pregnant and lactating women as well as mothers of malnourished children (WAZ <-2 zscores) between 6 and 59 months of age. A total of 18 months of enrollment was possible in this program arm.

干预措施: Fortified food rations (Dietary Supplement)

Preventive targeting

Experimental

This arm targeted pregnant and lactating women as well as children 6-23.9 months of age to receive BCC and food assistance. A total of 27 months of enrollment in this program arm was possible.

干预措施: Fortified food rations (Dietary Supplement)

Preventive targeting

Experimental

This arm targeted pregnant and lactating women as well as children 6-23.9 months of age to receive BCC and food assistance. A total of 27 months of enrollment in this program arm was possible.

干预措施: Education and communication to improve feeding practices (Behavioral)

Recuperative targeting

Active Comparator

This arm targeted pregnant and lactating women as well as mothers of malnourished children (WAZ <-2 zscores) between 6 and 59 months of age. A total of 18 months of enrollment was possible in this program arm.

干预措施: Education and communication to improve feeding practices (Behavioral)

结局指标

主要结局

Prevalence of undernutrition (stunting, wasting, underweight) two years after implementation of intervention

Mean z-scores (height-for-age, weight-for-age, weight-for-height) two years after intervention implemented

次要结局

  • Feeding practices and other caregiving practices at 2 years after implementation of intervention
  • Maternal knowledge about child feeding practices recommended through behavioral intervention at 2 years after implementation of intervention;

研究者

研究点 (1)

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