Sexual function in women with Polycystic Ovary Syndrome
Recruiting
- Conditions
- polycystic ovary syndrome1001470110040480
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 356
Inclusion Criteria
diagnosis of PCOS and age-matched controls (healthy women)
age: 18-40 years
stable heterosexual relationship for at least 6 months
Exclusion Criteria
a psychiatric disorder, pregnancy or lactation, having undergone a radical
hysterectomy or prolaps surgery, current or recent use of medication or medical
disorders (other than PCOS) that may influence sexual response.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1. General sexual function as measured with the FSFI, SDI, FSDS-R<br /><br>2. Genital sexual responsiveness (VPA) and self-reported ratings of subjective<br /><br>sexual responsiveness and affect (7 point Likert scale) from the<br /><br>psychophysiological measurements. </p><br>
- Secondary Outcome Measures
Name Time Method <p>1. The association between OCP use and general sexual function and genital<br /><br>sexual responsiveness.<br /><br>2. The association between sexual parameters as measured with SESII-W, SPAQ and<br /><br>SES and genereal sexual function and genital sexual responsiveness.<br /><br>3. Psychosocial parameters as measured with MBSRQ-AS, BISS, HADS, RSES and R-DAS<br /><br>4. Steroid hormone levels (Testosterone, Sex Hormone Binding Globluline (SHBG)<br /><br>calculating Free Androgen Index: Testosterone x 100/SHBG), Oestradiol,<br /><br>Progesterone, Luteinizing-hormone (LH), FollicleStimulating-hormone (FSH),<br /><br>Androstedione, Dehydro-epiandrosterone (DHEA), Dehydro-epiandrosterone sulphate<br /><br>(DHEAS), Thyroid Stimulating Hormone (TSH), Prolactine, and fasting glucose and<br /><br>insulin)<br /><br>5. Androgen receptor sensitivity as measured with CAG repeats</p><br>