Histopathological Examination of Iris Tissue in Buphthalmos

Not Applicable

Completed

• Conditions: Iris Disease
• Interventions: Procedure: Combined trabeculotomy trabeculectomy with mitomycin C

• Registration Number: NCT04011878
• Lead Sponsor: Assiut University

Brief Summary

To revise the etiology of the primary congenital glaucoma in some infants.

Detailed Description

Combined trabeculotomy trabeculectomy with mitomycin C was done in 11 eyes. Histopathological examination of the peripheral iris tissue specimen was done in all cases.

Study Timeline

• Study Start: 2016-01
• Primary Completion: 2018-10
• Study Completion: 2018-10
• Status Verified: 2019-07
• Study First Submitted: 2019-07-04
• Study First Submitted QC: 2019-07-04
• Last Update Submitted: 2019-07-04
• Study First Posted: 2019-07-09
• Last Update Posted: 2019-07-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• infants under age of 2 years
• 1ery glaucoma

Exclusion Criteria

• infants more than 2 years
• 2ery glaucoma
• previous glaucoma surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
isolated trabeculodysgensis	Combined trabeculotomy trabeculectomy with mitomycin C	etiology of primary congenital glaucoma

Primary Outcome Measures

Name	Time	Method
fibrovascular membrane over iris surface	6 month	angle closure by a fibrovascular tissue proliferation over the trabecular meshwork in the anterior chamber angle.