Arterial properties of ulcerative colitis patients and unaffected controls; a cross-sectional outpatient clinic study.

Recruiting

• Conditions: Ulcerative colitis; inflammatory bowel (colon) disease; 10017969; 10003816; 10003216

• Registration Number: NL-OMON51814
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

Ulcerative colitis, clinically in remission
>18 years of age

Exclusion Criteria

Age <18 years
Active UC

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Endothelial function as assessed by brachial artery flow mediated dilatation<br /><br>(FMD).<br /><br><br /><br><br /><br>Statistical analyses.<br /><br><br /><br>Brachial Flow mediated dilatation (FMD, %) is the primary endpoint of the<br /><br>study. FMD*s of the UC group and controls will be compared. For normally<br /><br>distributed data an (un)paired Student*s t-test will be used. The Wilcoxon or<br /><br>Mann-Whitney U test will be used for non-normally distributed data. A p-value<br /><br>of < 0.05 is considered statistically significant.</p><br>