KCT0008336
Not yet recruiting
未知
The efficacy and safety of clonal mesenchymal stem cell therapy for Hutchinson-Gilford Progeria syndrome
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Endocrine, nutritional and metabolic diseases
- Sponsor
- Inha University Hospital
- Enrollment
- 1
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Genetically confirmed Hutchinson\-Gilford progeria syndrome (progeria in childhood)
- •2\. Typical clinical symptoms of progeria identified by medical staff in this clinical study
- •3\. Aspartate aminotransferase (AST) and alanine aminotransfers (ALT) at the time of enrollment/screening \< 5× upper limit of normal
- •4\. Research subjects and legal representatives who must be able to visit the center according to this research plan and who are willing to participate voluntarily
Exclusion Criteria
- •Research subjects who fall under any of the following are excluded from the study.
- •1\. Severe renal impairment (GFR \< 30ml/min/1\.73m2\)
- •2\. Other clinical study medications received 90 days prior to the first treatment visit
- •3\.Persons with serious adverse reactions during stem cell treatmen
- •4\. In the case of a medical condition that prevents safe participation in the study according to the opinion of the research director
Outcomes
Primary Outcomes
Not specified
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