Maintenance of baroreflex sensitivity during intravenous sedation with a combination of propofol and midazolam
Not Applicable
- Conditions
- mentally handicapped patient dental phobia
- Registration Number
- JPRN-UMIN000004058
- Lead Sponsor
- Matsumoto Dental University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with serious circulatory or respiratory diseases, epilepsy, egg or buckwheat allergies, or any other serious chronic diseases were excluded from experiments.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method For analysis of spontaneous baroreflex sensitivity, we examined continuous finger arterial pressure and electrocardiograms to detect sequence changes in the R-R interval with parallel changes in arterial pressure. Our software selected all of the sequences of three or more successive heart beats in which there were concordant increases or decreases in systolic blood pressure and R-R intervals. A linear regression was applied to each of the sequences, and the mean slope during each condition was assessed as baroreflex sensitivity.
- Secondary Outcome Measures
Name Time Method