Multicenter Retrospective Observational Study to Verify the Application of SIE/SIES/GITMO FITNESS CRITERIA to Guide Therapeutic Choice in Elderly Patients With Acute Myeloid Leukemia in Light of the Availability of New Drugs - AML FITNESS
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 725
- 试验地点
- 1
- 主要终点
- overall survival according to fitness categories and treatment received
研究概览
简要总结
The study aims to evaluate the outcome of patients (overall survival) who received treatments commensurate with the proposed "Fitness" parameters compared to that of patients whose treatment differed either in the direction of greater or lesser aggressiveness than that proposed (evaluation of survival through Kaplan-Meier analysis and comparison with the log-rank test).
详细描述
Evaluate adherence to SIE/SIES/GITMO criteria in therapeutic choice: assess the treatment actually received by the different patient groups and any deviations from those proposed (descriptive statistics)
- Evaluate whether the SIE/SIES/GITMO criteria are still current after the introduction of new drugs (descriptive statistics)
- Evaluate the treatment actually received by the different patient groups and any deviations from those proposed
- Evaluate the possibility of potentially identifying new criteria to better define fitness categories in light of the therapy actually administered to the patient (descriptive statistics)
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute Myeloid Leukemia Diagnosis no Acute Promyelocytic Leukemia aged more than 65 years
排除标准
- 未提供
结局指标
主要结局
overall survival according to fitness categories and treatment received
时间窗: "From enrollment to the end of treatment at 12 months"
次要结局
未报告次要终点
研究者
Erika Borlenghi
Dr.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia