Mamma Board Project: Prone Breast Irradiation for Pendulous Breasts

Maastricht Radiation Oncology1 site in 1 country10 target enrollmentDecember 2003

ConditionsBreast Cancer

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Breast Cancer
Sponsor: Maastricht Radiation Oncology
Enrollment: 10
Locations: 1
Primary Endpoint: Dose Homogeneity 1: PTV
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

We hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart.The purpose of this study is to compare the 3-D dose distribution in PTV(Planning Target Volume) and normal tissues in prone position versus supine position.

Detailed Description

Local excision followed by adjuvant radiotherapy has become standard treatment for women with early-stage breast cancer. Adjuvant radiotherapy may encounter technical difficulties in patients with pendulous breasts when treated in supine position. Based upon literature and our own preliminary experiences, we hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart. However, no quantitative data are yet available to test this hypothesis. Therefore, the aim of our study is to compare the 3-D dose distribution in PTV and normal tissues in prone position versus supine position. For treatment in prone-position an in-house developed device, the "mammaboard" was used.

Registry

clinicaltrials.gov

Start Date

December 2003

End Date

January 2007

Last Updated

6 years ago

Study Type

Interventional

Study Design

Single Group

Sex

Female

Investigators

Sponsor

Maastricht Radiation Oncology

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients should have had breast-conserving surgery for breast cancer or DCIS (Ductal Carcinoma in Situ)
•No indication for radiotherapy of regional nodes
•Large, pendulous breasts (bra size D and over)