Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery
Phase 3
Completed
- Conditions
- Prevention of Postoperative Ileus
- Interventions
- Drug: Placebo Oral Tablet
- Registration Number
- NCT03477266
- Lead Sponsor
- Benha University
- Brief Summary
Giving women one day before and immediately after cesarean section a mouthly dissolving mosapride tablets 2every every 8 hours for maximum of 5 days ,or getting recovered gastrointestinal functions And assess preoperative gastrointestinal functions
- Detailed Description
Uncomplicated post cesarean women one day before and immediately after elective cesarean receive 2 mouthly dissolving mosapride tablets every 8 hours maximum for 5 days and clinical care giver follow the woman's gastrointestinal functions, including intraoperative and postoperative nausea vomiting, passing flatus, hearing intestinal sounds, passing stools, occurring of paralytic ileus, length of the hospital stay
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 400
Inclusion Criteria
- all women undergoing elective cesarean section
Exclusion Criteria
- prior abdominal surgery, abdominal adhesion, chronic constipation, allergy to mosapride
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo mouth dissolving tablets Placebo Oral Tablet Dummy identical tablets taken in the same way Mouth dissolving mosapride Mosapride Fluxopride 5mg of Macryrl egypt 2 tablets one day before and immediately after elective cesarean section every 8hour for maximum of 5 days
- Primary Outcome Measures
Name Time Method Time of first flatus 96 hours postoperative Clinical
- Secondary Outcome Measures
Name Time Method Paralytic ileus incidence and its severity 7days Clinical
Toleration of fluids and solids intake 2 weeks postoperative Clinical
Incidence of intraoperative and postoperative nausea and vomiting Intraoperative and 2 weeks postoperative Clinical
First defecation 2 weeks postoperative Clinical
Trial Locations
- Locations (1)
Ashraf nassif Elmantwe
🇪🇬Banha, Elqalopia, Egypt