An observational comparative study to evaluate the ocular changes in patients undergoing spine surgery in prone position under Total Intravenous Anaesthesia versus Balanced Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Measure the Intraocular pressure at various intervals in both groups to observe and compare the better outcome of ocular changes
研究概览
简要总结
We propose to conduct a observational comparative study of the ocular pressure changes- intraocular pressure(IOP),mean arterial pressure( MAP) ,ocular perfusion pressure(OPP) in patients undergoing spine surgery in prone position when maintained intraoperatively under Total intravenous anaesthesia versus Balanced Anaesthesia. Prone position is used for posterior approach in spine surgery, such positioning is known to cause ocular changes due to pressure on the orbital content and the altered hemodynamics(MAP) leading to increase intraocular blood volume thus IOP and OPP; hypoxia to optic nerve, ischemic optic neuropathy ,visual loss are some of the ocular changes observed. Thus the study is done in comparison to establish a protocol to prevent and anticipate the ocular changes. Patients will undergo pre anaesthetic checkup prior to surgery. Informed consent will be obtained from patients who meet the inclusion criteria. We will measure IOP, MAP, HR before induction, 5 min after induction and at the end in supine position, 5 min after extubation then OPP will be calculated from IOP and MAP, post-operative outcome and any adverse events during the surgery will be recorded.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients undergoing spine surgery (thoracolumbar)
- •Less than 4 hours duration of surgery
- •Prone position 4.
排除标准
- •Refusal to consent for proposed study,
- •ASA III &IV
- •Any history of Glaucoma
- •Any ocular surgery(less than 3 months)
- •Cervical spine surgery 6.
结局指标
主要结局
Measure the Intraocular pressure at various intervals in both groups to observe and compare the better outcome of ocular changes
时间窗: IOP1-before induction | IOP2- 5 min After induction | IOP3- 5 min After Supine position at the end of surgery | IOP4- 5 min After extubation
次要结局
- heart rate, mean arterial pressure,SpO2(Time(mins))
研究者
DR SANDHYA B K
M S RAMAIAH MEDICAL COLLEGE AND HOSPITAL(RUAS)
