Relevamiento / Encuesta Nacional de Infarto Agudo de Miocardio Con elevación Del ST
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- Appropriate use of reperfusion therapy
研究概览
简要总结
Aim of investigators is to conduct a registry of acute myocardial infarction including a broad network of critical care / coronary care unit throughout Argentina to increase the knowledge about treatments, timing of reperfusion therapy and outcomes, both in-hospital and during short-term follow up.
详细描述
Cardiovascular disease is the most common cause of death in the world and in Argentina, as well as a cause of disability and loss of work capacity in adults. Treatment of various forms of serious diseases such as acute ischemic events and heart failure are now supported by scientific studies and allow a markedly reduction in disability and mortality. Access to diagnostic and therapeutic strategies require proper coordination of the health system and far exceed the role of specialists. Given the frequency of these diseases, it is essential to have information on the prevalence and treatment, and the various barriers to access to diagnosis and appropriate treatment. Both for the basic knowledge to evaluate the relevance and effectiveness of corrective action a record of pathologies is required, with information accurate enough to enable the adoption of public policies, and adjusted to national needs.
Scientific societies in cardiovascular field, Argentine Society of Cardiology and Argentine Federation of Cardiology, have a long history of registers and educational programs to improve cardiovascular care. However, these tasks are limited to institutions with academic programs and probably do not reach the majority of our population.
A national survey of high prevalence of cardiovascular diseases, starting with acute myocardial infarction with ST segment elevation, together with the authorities of the National Ministry of Health, would put Argentina at the level of most developed countries in this subject. Knowledge of general and local barriers will allow a rapid implementation of corrective measures and the evaluation of their impact through the permanent record. Improving the quality of cardiovascular patient care, optimizing adherence to standards of diagnosis and treatment can be achieved through different paths as self-knowledge of the institutions of their level of performance and dissemination of coordination measures, generating systematic referral and care networks, diagnostic support systems such as telemedicine, and others that can be assessed globally or regionally according to the identified problems.
Networking will also enable the implementation of initiatives that will result in an increase in the quality of care and generate epidemiological research projects that enhance patient care and outcomes. In conclusion, it will allow to know the problems in depth and adopt measures to improve the quality of care and reduce morbidity and mortality.
The main objective of the survey is to register at national level, in the broadest possible way trying to reach the "universe" of care for this disease in Argentina, aspects of clinical, delays, treatment schedules and results, with sufficient information to quickly allow the adoption of policies to improve the quality of care and subsequent control.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted with AMI and ST-segment elevation.
- •AMI evolved with new Q waves less than 36 hours evolution.
- •Suspected inferoposterior AMI (horizontal ST depression in V1 to V3, suggestive of acute circumflex coronary artery occlusion).
- •New or presumed new left bundle branch block.
排除标准
- •Acute coronary syndrome without ST elevation or non-Q AMI
- •Myocardial infarction of more than 36 hours of evolution.
结局指标
主要结局
Appropriate use of reperfusion therapy
时间窗: In-hospital, with an expected average of 5 days.
Timely initiation of reperfusión (door to needle time \<30 minutes or door to balloon time \<90 minutes).
In-hospital mortality
时间窗: In-hospital, with an expected average of 5 days.
All cause death during initial hospitalization.
All cause mortality
时间窗: 30 days.
All cause mortality between symptoms onset and 30 days.
次要结局
- In-hospital complications(In-hospital, with an expected average of 5 days.)
