Efficacy Evaluation of Triple up® Collagen Drink on Skin Condition

Not Applicable

Completed

• Conditions: Skin Condition
• Interventions: Dietary Supplement: Blank; Dietary Supplement: Testing product

• Registration Number: NCT04225091
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess Triple up® Collagen Drink on skin condition improvement

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-01-06
• Study First Submitted QC: 2020-01-08
• Study First Posted: 2020-01-13
• Study Start: 2020-01-30
• Primary Completion: 2020-04-21
• Study Completion: 2020-05-07
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-27
• Last Update Posted: 2020-11-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Healthy adults aged above 20 years old

Exclusion Criteria

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
• Vegetarian
• Subjects who have large spots (area >3 square centimeter) or abnormal acne.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo drink	Blank	-
Triple up® Collagen Drink	Testing product	-

Primary Outcome Measures

Name	Time	Method
The change of skin collagen density	Change from Baseline skin collagen density at 4 weeks	DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score
The change of skin moisture	Change from Baseline skin moisture at 4 weeks	Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin elasticity	Change from Baseline skin elasticity at 4 weeks	Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves
The change of skin wrinkles	Change from Baseline skin wrinkles at 4 weeks	VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units

Secondary Outcome Measures

Name	Time	Method
The change of skin texture	Change from Baseline skin texture at 4 weeks	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin pores	Change from Baseline skin pores at 4 weeks	VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

Trial Locations

Locations (1)

Chia Nan University of Pharmacy ＆ Science; 🇨🇳 Tainan, Taiwan