Taste and Smell Alterations and Oral Nutritional Supplement (ONS) Preferences in Patients With Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Flavor liking of five different oral nutritional supplement flavors.
研究概览
简要总结
Patients diagnosed with cancer have a particularly high risk of developing malnutrition due to the disease itself and due to symptoms of cancer treatments that can affect food intake such as reduced appetite, nausea, fatigue, and alterations in taste and smell. Nutritional treatment is essential in the prevention and treatment of malnutrition. Oral nutritional supplements (ONS) are often recommended to cancer patients who need to increase their nutritional intake and are unable to meet their nutritional requirements by consumption of normal food alone. However, patient compliance with ONS depends on sensory acceptability of such products. Therefore, the objective of this study is to investigate preferences of sensory characteristics of ONS among cancer patients. Additionally, possible associations between taste and smell alterations and dietary intake, malnutrition risk, and quality of life will be investigated. The results from this study will optimize recommendations of ONS in the clinical setting and encourage new efforts among manufacturers in developing acceptable sensory characteristics of ONS to cancer patients. Findings from this study will contribute to improving nutritional treatment for cancer patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ambulatory patients diagnosed with lung cancer
- •Patients receiving cancer treatment of different types
- •Age 18 years or more
- •Provided signed informed consent
- •Understand written and oral Norwegian
排除标准
- •Severe mental or cognitive disorders
- •Contraindication to consume ONS (dysphagia, inability to swallow oral nutritional supplements)
- •Allergic or intolerant to any of the ingredients in the ONS
- •Terminally ill patients (<3 months to live)
- •A clinically significant disease or condition that could, in the investigator's opinion make the patient unfit for the study
结局指标
主要结局
Flavor liking of five different oral nutritional supplement flavors.
时间窗: 30 minutes
To evaluate patient liking of five different oral nutritional supplement flavors using a taste test and a questionnaire with a 9-point Hedonic scale (possible score from 1 to 9) assessing flavor liking. A higher score indicates better liking.
次要结局
- Quality of life.(10 minutes)
- Liking of ONS characteristics with and without the presence of taste and smell alterations by the 16-item questionnaire Taste and Smell Survey (TSS).(30 minutes)
- Self-reported taste and smell alterations.(10 minutes)
- Prevalence of malnutrition risk.(5 minutes)
- Dietary intake.(3 days)
- Flavor liking with and without the presence of taste and smell alterations by the 16-item questionnaire Taste and Smell Survey (TSS).(30 minutes)