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临床试验/NCT03300245
NCT03300245Unknown不适用

The Relationship Between the Direction and Degree of Nasal Septal Deviation and Nasal Bone Morphology

Assiut University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2018年8月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
50
试验地点
1
主要终点
The nasal deviation angle

研究概览

简要总结

The aim of the study is to evaluate the relationship between the direction and degree of nasal septal deviation with nasal bone morphology , along with factors such as age and gender.

详细描述

The nasal septum is located in the middle of the nasal cavity and it forms the major part of the nose structure. It is divided into a posterior part by the vomer and perpendicular plate of the ethmoid bone and an anterior part by the quadrangular cartilage .

In the growth period, the nasal septum acts as a growth plate that affects surrounding bones and facial skeletal tissues .Thus, nasal septum deviation affects facial morphologic parameters such as interalveolar distance and maxillary rotation distance, causing compensatory changes in the lateral nasal wall and septal deviation,which are associated with nasal floor and palatal region asymmetries .

Nasal septum deviation is the most common anatomic variation in up to 80% of healthy adults .

From the initial growth stages, the maxillary bone and nasal structure have significant anatomic connections because of their close embryologic development.

The severity of septal deviation also affects the ipsilateral lateral lamina of the cribriform plate width and ipsilateral middle turbinate length . Nasal septal deviation may affect nasal bone growth and facial morphology .Knowledge of nasal morphologic parameters plays an important role in planning successful rhinoplasty and septoplasty operations.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients over 18 years old who attending to Ear,Nose and throat department out patients complaining of nasal septum deviation causing nasal symptoms are exposed to maxillofacial CT.

排除标准

  • Patients with a history of rhinoplasty,
  • Patients with cranial and facial trauma or bone deformity (e.g. S-shaped septum deviation).
  • Patients with a mass or polyp in the nasal cavity.
  • Patients with adenoid .
  • Patients with nasopharyngeal lesions.
  • Patients with craniofacial anomalies.

结局指标

主要结局

The nasal deviation angle

时间窗: 10 minutes

It will be measured on coronal CT images as the angle between the most deviated point of the septum and the midline which is the line from the crista galli to the palatum

Nasal bone length

时间窗: 10 minutes

The nasal bone length will be measured from frontonasal suture to the endpoint of the nasal bone on the sagittal plane

Internasal angle

时间窗: 10 minutes

The internasal angle will be measured on coronal CT images at the site of the nasion point

The lateral and intermediate nasal bone thickness

时间窗: 10 minutes

The nasal bone thickness will be measured in axial images at the site of the lateral and intermediate osteotomy lines. The lateral osteotomy lines run along nasomaxillary suture and intermediate (or midline) osteotomy lines runs along the internasal suture. The lateral nasal bone thickness will be measured at the nasomaxillary suture. Intermediate nasal bone thickness was measured at the midpoint between the nasomaxillary suture and the rhinion .

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Martina Boshra Shawky

principal investigator

Assiut University

研究点 (1)

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