Preliminary Establishment of the Medical Reference Range of Serum Vitamin K2 in Chinese Healthy Adults
- Conditions
- Health, Subjective
- Registration Number
- NCT05436483
- Lead Sponsor
- Peking University Third Hospital
- Brief Summary
Osteocalcin is a type of vitamin K2-dependent protein, and many studies have confirmed that vitamin K2 has anti-osteoporosis effects, and has preventive and therapeutic effects on a variety of diseases such as nervous system, cardiovascular disease, immune disease, and glucose metabolism. However, as a pleiotropic vitamin and nutrient, vitamin K2 does not have an exact normal range like other vitamins, when it needs to be supplemented, and in what regimen. Different organizations have different opinions on the recommended intake of vitamin K. Thus, this study intends to preliminarily obtain the reference interval of serum vitamin K2 by conducting clinical research in healthy people in the Beijing-Tianjin-Hebei region, and analyzes different factors, such as gender, age, and place of residence, to compare their level differences and changing trends, and to provide data reference for the recommended intake of vitamin K2 for people with vitamin K2 deficiency.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 465
- People aged over 18.
- People with normal routine blood test.
- Willing to participate in this study.
- Subjects with congenital metabolic problems and endocrine diseases.
- Treatment with any investigational drug within the past 3 months.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concentration of vitamin K2 During the procedure of regular physical checkups Vitamin K2 concentration in serum
- Secondary Outcome Measures
Name Time Method