Comparison of two different low doses of ondansetron in combination with dexamethasone for prevention of postoperative nausea and vomiting in middle ear surgery
Phase 4
Completed
- Conditions
- Health Condition 1: - Health Condition 2: K929- Disease of digestive system, unspecified
- Registration Number
- CTRI/2019/02/017523
- Lead Sponsor
- niversity College of Medical Sciences and GTB Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged 16-65 years of either sex, with ASA physical status I or II,
undergoing middle ear surgery (tympanoplasty or mastoidectomy) under GA
Exclusion Criteria
Pregnant patients
Patients who received other antiemetic medication or perioperative steroids as
anti-edema therapy for facial nerve damage
Patients having history of cardiac, hepatic and renal disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PONV scoreTimepoint: In the fisrt 2 hrs, 2-6 hrs, 6-12 hrs and 12-24 hrs
- Secondary Outcome Measures
Name Time Method HR, SBP, DBP and MAPTimepoint: Every 15 minutes in the postoperative period for first 4 hrs;Total rescue antiemetic consumptionTimepoint: at the end of 24 hrs