The effect of the oral probiotic on some parameters of the vaginal health
- Conditions
- Vaginal health.Foreign body in vulva and vagina
- Registration Number
- IRCT2015062322892N1
- Lead Sponsor
- Vice chancellor for Research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
The age 18-55 years; married; nonpregnant women; willing to participate in study; having natural menstrual cycles; nonsmokers; Nugent score = 4-6; pH >4.5; clinically, the samples not suffered any vaginitis; not suffered from such disease as liver, heart, kidney, diabetes, nervous system ailments, immunodeficiency, sexually transmitted illnesses; non-abnormal vaginal bleedings
Exit criteria:
pregnancy occurrence during the study; the use of vast spectrum antibiotics, hormonal drugs, alcohol, anticoagulation drugs and the recent month immunosuppressive; infection existence; ulcers, injury and abnormal secretions in the vulve, vagina and cervix examinations; sensitivity symptoms against oral probiotic; suspension with going on the study participation
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vaginal pH. Timepoint: respectively after 10, 30, 60 and 70 days of consuming probiotic or placebo in two study groups. Method of measurement: Test strip Merck Germany.;Nugent score. Timepoint: respectively after 10, 30, 60 and 70 days of consuming probiotic or placebo in two study groups. Method of measurement: Take smear from vagina with a cotton swab and make a direct smear on a microscope slide . In the laboratory the smears were stained and observed under the microscope to estimate nugent score.;Lactobacillus colonization of vagina. Timepoint: respectively after 10, 30, 60 and 70 days of consuming probiotic or placebo in two study groups. Method of measurement: Coun Lactobacillus.
- Secondary Outcome Measures
Name Time Method