Polarized Light Therapy in Patients With CREST Syndrome.

Not Applicable

Completed

• Conditions: CREST Syndrome
• Interventions: Other: stretching, strengthening exercises and active exercises

• Registration Number: NCT06621628
• Lead Sponsor: New Ismailia National University

Brief Summary

to evaluate the efficacy of the Polarized light therapy and Hand Grip Strengthening exercises in patients with CREST syndrome

Detailed Description

Measurement of the skin thickness via the modified Rodnon skin score (RSS) and Hand Grip Dynamometer (HGD) . Methods:- Sixty patients, who had hand involvement of patients with CREST syndrome, were participated in the study. Their ages were ranged from 16 to 45 years. The participants were selected from the dermatology departments of Cairo university hospitals and Om El-Misrieen hospital, randomly distributed into three equal groups. Group A: (Study group): This group included 20 patients who had CREST syndrome with scleroderma in the dorsum of hands and who received the BLT with traditional physical therapy program (stretching, strengthening and active exercise) patients received 3 sessions per week for 12 weeks (3 months),time of session is 15 minutes. Group B: This group included 20 patients who have CREST syndrome with scleroderma in the dorsum of hands and who received resisted exercise with traditional physical therapy program (stretching, strengthening and active exercise) patients received 3 sessions per week for 12 weeks (3 months), time of session is 15 minutes and Group C:This group included 20 patients who had CREST syndrome with scleroderma in the dorsum of hands and who received combination of (BLT and resisted exercise) with traditional physical therapy program (stretching, strengthening and active exercise) exercise program (stretching, strengthening and active exercise).patients received 3 sessions per week for 12weeks (3 months), time of session was 15 minutes.

Study Timeline

• Study Start: 2023-04-10
• Primary Completion: 2023-07-01
• Study Completion: 2024-07-05
• Status Verified: 2024-09
• Study First Submitted: 2024-09-26
• Study First Submitted QC: 2024-09-28
• Last Update Submitted: 2024-09-28
• Study First Posted: 2024-10-01
• Last Update Posted: 2024-10-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• The patients' ages ranged from 16 to 21 years.
• Patients who had hand involvement of patients with CREST syndrome particularly dorsum of the hand.
• All patients were conscious.
• All patients were randomly chosen (male and female).

Exclusion Criteria

• Patients who are diabetic or hypertensive.
• Patients those familiar with the BLT and resisted exercise via the hand grip strengthener.
• Patients with hemorrhage specially hemorrhage of digestive system and those with bleeding per rectum.
• Patients with severe fungal diseases and acute viral diseases.
• Patients with active tuberculosis and tumors as well as those with peacemakers.
• Patients with polyneuropathy.
• Patients with thyroid problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group A	stretching, strengthening exercises and active exercises	This group included 20 patients who had CREST syndrome with scleroderma in the dorsum of hands and who received the BLT with traditional physical therapy program (stretching, strengthening and active exercise) patients received 3 sessions per week for 12 weeks (3 months),time of session is 15 minutes.
study group B	stretching, strengthening exercises and active exercises	This group included 20 patients who have CREST syndrome with scleroderma in the dorsum of hands and who received resisted exercise with traditional physical therapy program (stretching, strengthening and active exercise) patients received 3 sessions per week for 12 weeks (3 months), time of session is 15 minutes
study group C	stretching, strengthening exercises and active exercises	This group included 20 patients who had CREST syndrome with scleroderma in the dorsum of hands and who received combination of (bipotron light therapy and resisted exercise) with traditional physical therapy program (stretching, strengthening and active exercise) exercise program (stretching, strengthening and active exercise).patients received 3 sessions per week for 12weeks (3 months), time of session is 15 minutes

Primary Outcome Measures

Name	Time	Method
skin thickness	12 weeks	modified random skin score
hand grip strength and pinch gauge	12 weeks	Hand dynamometer

Trial Locations

Locations (2)

Khadra Mohamed Ali; 🇪🇬 Ismailia, Egypt

Mohamed Abdel Moenem Abo El Ros; 🇪🇬 Ismailia, Egypt