The Perioperative Administration of Dexamethasone and Glucose concentrations in diabetic and non-diabetic surgical patients

Phase 4

Completed

• Conditions: Diabetes Mellitus; Surgery; Anaesthesiology - Anaesthetics; Metabolic and Endocrine - Diabetes; Surgery - Other surgery

• Registration Number: ACTRN12614001145695
• Lead Sponsor: Royal Perth Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-10-29
• Last Update Posted: 26 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 700

Inclusion Criteria

Elective surgical patients
Skin incision required
Surgical duration greater than one hour
At least one night hospital stay postoperatively
General anaesthesia
ASA grade 1-4

Exclusion Criteria

Pure regional anaesthesia
Hypersensitivity to study drug
Poorly controlled Type 1 diabetes mellitus
Sickle cell anaemia
Thalassemia
Surgical procedure within the previous 3 months
Surgical procedure planned within 30 days of the index procedure
Infection within three months prior to procedure
Maxillofacial surgery
Intraoperative requirement
Renal Impairment
Immunosuppressive therapy or state
Concurrent systemic glucocorticoid usage
Moderate or severe liver disease
Metastatic cancer
Opthalmic surgery
Endovascular procedures

Study & Design

• Study Type: Interventional
• Study Design: Not specified