A multicenter randomized controlled trial on early fluid resuscitation in extensively burned patients.
- Conditions
- Burn
- Registration Number
- JPRN-UMIN000019740
- Lead Sponsor
- Japanese Association for Acute Medicine Japanese Society for Burn Injuries
- Brief Summary
There were no statistically significant differences between the 2 groups in the serum creatinine, and acute kidney injury based on the KDIGO guideline within 48 h after arrival at the hospital, survival rate on the 28th day, and discharge survival rate. The Modified Brooke formula group failed to achieve the target urine output corresponding to the infusion volume within 8 h after arrival, especially in more than 40% TBSA burn patients, but it did not become a clinical problem.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 39
Not provided
Cardiopulmonary arrest Chemical burn Electric burn Case with time interval beyond 4 hours after burn Case received fluid resuscitation before the arrival Comorbidity; heart disease, COPD, chronic renal failure, hepatic cirrhosis. Case combined trauma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method