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Evaluating role of Adaptive radiotherapy in head neck cancers in reducing salivary gland toxicity

Phase 3
Conditions
Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Registration Number
CTRI/2018/08/015531
Lead Sponsor
Tata Memorial Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Biopsy proven Squamous cell carcinoma of the oropharynx, hypopharynx and larynx.

2.AJCC stage T1-3, N0-2c, M 0.

3.KPS >= 70.

4.Age >=18 and <= 70 years.

5.Patient willing and reliable for follow-up.

6.Patientâ??s nutritional & physical condition compatible with planned therapy.

7.Signed study specific consent form.

Exclusion Criteria

1.T1-2 N0 M0 of Vocal cords

2.History of surgery for the primary or node in head and neck.

3.Evidence of distant metastases or N3 nodal stage.

4.Previous therapeutic irradiation for head & neck cancer.

5.Patients who have received neoadjuvant chemotherapy.

6.Active untreated infection, which preclude the use of systemic chemotherapy or would interfere with completion of treatment.

7.Any histopathology other than Squamous Carcinoma.

8.Primary nasopharyngeal or paranasal sinus cancers.

9.Pregnancy or lactating women.

10.Previous history of malignancy within 5 years.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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