Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease
Not Applicable
- Conditions
- Moyamoya Disease
- Interventions
- Other: bypass surgery and indrect bypass surgery
- Registration Number
- NCT02982135
- Lead Sponsor
- liuxingju
- Brief Summary
The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- cerebral digital subtraction contrast angiography (DSA) revealed severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate "moyamoya collaterals"
- patients had experienced at least one intracranial hemorrhage which was verified by computed tomography (CT) scanning, magnetic resonance imaging MRI), or lumbar puncture.
- Patients requiring surgery
Exclusion Criteria
- Patient whose initial onset was marked by ischemia but subsequently suffered from intracranial hemorrhage
- patients refused to participate in the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description group 1 direct bypass bypass surgery and indrect bypass surgery direct bypass : patients recieve direct bypass treatment group 2 indirect bypass bypass surgery and indrect bypass surgery indirect bypass: patients recieve indirect bypass treatment
- Primary Outcome Measures
Name Time Method rebleeding events 5-10 years
- Secondary Outcome Measures
Name Time Method ischemic events 5-10 years postoperative compilications 30 days
Trial Locations
- Locations (1)
Beijing Tiantan Hospital Capital Medical University
🇨🇳Beijing, Beijing, China