Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease:a Prospective Multi-center Cohort Study

liuxingju1 site in 1 country300 target enrollmentJanuary 2016

ConditionsMoyamoya Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Moyamoya Disease
Sponsor: liuxingju
Enrollment: 300
Locations: 1
Primary Endpoint: rebleeding events
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.

Registry

clinicaltrials.gov

Start Date

January 2016

End Date

January 2018

Last Updated

9 years ago

Study Type

Interventional

Study Design

Factorial

Sex

All

Investigators

Sponsor

liuxingju

Responsible Party

Sponsor Investigator

Principal Investigator

liuxingju

Principal investigator

Ministry of Science and Technology of the People´s Republic of China

Eligibility Criteria

Inclusion Criteria

•cerebral digital subtraction contrast angiography (DSA) revealed severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate "moyamoya collaterals"
•patients had experienced at least one intracranial hemorrhage which was verified by computed tomography (CT) scanning, magnetic resonance imaging MRI), or lumbar puncture.
•Patients requiring surgery

Exclusion Criteria

•Patient whose initial onset was marked by ischemia but subsequently suffered from intracranial hemorrhage
•patients refused to participate in the study