Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease

Not Applicable

• Conditions: Moyamoya Disease

• Registration Number: NCT02982135
• Lead Sponsor: liuxingju

Brief Summary

The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Status Verified: 2016-11
• Study First Submitted: 2016-11-20
• Study First Submitted QC: 2016-12-02
• Last Update Submitted: 2016-12-02
• Study First Posted: 2016-12-05
• Last Update Posted: 2016-12-05
• Primary Completion: 2017-12
• Study Completion: 2018-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1. cerebral digital subtraction contrast angiography (DSA) revealed severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate "moyamoya collaterals"
2. patients had experienced at least one intracranial hemorrhage which was verified by computed tomography (CT) scanning, magnetic resonance imaging MRI), or lumbar puncture.
3. Patients requiring surgery

Exclusion Criteria

1. Patient whose initial onset was marked by ischemia but subsequently suffered from intracranial hemorrhage
2. patients refused to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
rebleeding events	5-10 years

Secondary Outcome Measures

Name	Time	Method
postoperative compilications	30 days
ischemic events	5-10 years

Trial Locations

Locations (1)

Beijing Tiantan Hospital Capital Medical University; 🇨🇳 Beijing, Beijing, China