Effect of the dual treatment of diquafosol sodium and rebamipide on dry eye syndrome related to chronic graft versus host disease and Sjogrens syndrome
Not Applicable
- Conditions
- Dry eye related to chronic GVHD and Sjogren s syndrome
- Registration Number
- JPRN-UMIN000013234
- Lead Sponsor
- Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1, Dry eye syndrome severity level 4 (dry eye workshop classification 2007) 2, Patients dosed diquafosol sodium and / or rebamipide ophthalmic solution 3, Patients having a concern of becoming severe dry eye because of having GVHD in other organs and so on 4, Patients with ocular pemphigoid, and Stevens-Johnson syndrome 5, Patients with a history of ophthalmic surgery within 6 months before the study 6, Patients wearing contact lens 7, Patients who will be applied radiation treatment during the study 8, Patients dosed cevimeline hydrochloride hydrate and /or pilocarpine(eye drop or oral drug) 9, Patients who will be ineligible for registration the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anterior ocular segment remark Corneal sensitivity Schirmer test Tear film breakup time Fluorescein staining Rose bengal staining Subjective symptom
- Secondary Outcome Measures
Name Time Method