Measurement of Skinfold Thickness in Subscapular Area to Monitor Hydration Status in Chronic Hemodialysis Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Medical University of Lodz
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- changes in overhydration
Study Overview
Brief Summary
Background Maintaining fluid balance is one of major challenges of the dialysis therapy. It includes, in particular, the management of "dry body mass". We postulated that simple measurement of subscapular skinfold thickness before and after hemodialysis could help monitor hydration status in chronic dialysis patients.
Aim of the study The aim of the study was to compare the conventional methods of monitoring hydration status during hemodialysis with an assessment of skin fold thickness.
Materials and Methods 50 participants (21 F, 29 M; age 60 ±15 years) were enrolled. Directly before the hemodialysis session the following parameters were measured: body composition with bioimpedance spectroscopy, skinfold thickness in subscapular area with standardized caliper and blood tests: blood count, urea, n-terminal pro B-type natriuretic peptide (nt-proBNP) and pro-adrenomedullin (pro-ADM). The procedures were repeated at the end of three consecutive hemodialysis sessions.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •chronic hemodialysis for at least 3 months
Exclusion Criteria
- •severe mental disabilities, poor compliance, any acute infection, instability of the cardiovascular hemodynamic condition
Arms & Interventions
changes of overhydration during hemodialysis session
Intervention: dialysisis with and without glucose in the dialysis (Procedure)
Outcomes
Primary Outcomes
changes in overhydration
Time Frame: From enrollment to one week
Secondary Outcomes
No secondary outcomes reported
Investigators
Michal Nowicki
Professor MD
Medical University of Lodz