Frequencies, Risk Factors and Outcome of Ventilation-Associated Lung Complications At Paediatric Intensive Care Unit (PICU)
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- assess right sided heart failure post ventilator acquired pneumonia
研究概览
简要总结
This study aims to determine the incidence, risk factors and outcome of ventilation associated common complication in the PICUs at Assiut University Children Hospital in Egypt.
详细描述
A constellation of adverse effects and complications may be associated with mechanical ventilation,The following are the Commonest Complications of Mechanical Ventilation
- Ventilator-associated pneumonia.
- Ventilator-induced lung injury.
- Ventilation induce Hemodynamic compromise leads to ARDS. Ventilator-Associated Pneumonia (VAP) It refers to nosocomial pneumonia occurring 48 hours or more after initiation of mechanical ventilation (MV)
It is the second most common HAI after blood stream infection in the paediatric age group, accounting for about 20% of all HAIs in the paediatric intensive care units (PICUs) and has a rate of 2.9- 21.6 per 1000 ventilator days.The risk factors responsible for VAP occurrence can be classified into:
A-Host related factors: include associated co-morbidities B-Device-related factors: include the endotracheal tube, the ventilation circuit, and the presence of a nasogastric or an orogastric tube.
C-Personnel related factors: include improper hand hygiene and inadequate use of personal protective equipment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Month 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children aged one month to up to 16 years Intubated and connected to MV for at least 48hrs.
排除标准
- •Neonates and cases connected to M.V less than 48 hours.
结局指标
主要结局
assess right sided heart failure post ventilator acquired pneumonia
时间窗: one year from april 2022 to april 2023
use modified ross score for evaluation of heart failure post mechanical ventilation
次要结局
- Asess the risk factors associated with barotrauma on mechanical ventilation(one year from april 2022 to april 2023)
研究者
Abdelrahman Mahmoud Ezzat
principle investigator
Assiut University